top of page

SCIENCE
Hiltonol Mimics Nature by Combining the Essential Elements of Human Immunity
Hiltonol® is a synthetic dsRNA viral mimic and host-defense activator
-
Hiltonol’s® tumor pro-apoptotic effect induces tumor antigen and neoantigen expression
-
Promotes induction of natural killer cells and dsRNA dependent systems (OAS, PKR)
-
-
Hiltonol® is the preferred critical 'Danger Signal', or Immune Adjuvant for Cancer Vaccines
-
§Mechanisms include TLR3 and MDA5 mediated systems
-
-
Hiltonol® induces killer-cell targeting (chemotaxis) and tumor vascular endothelial infiltration
-
Hiltonol® supports the hosts ability to overcome immune suppression ‘checkpoints’ in the tumor microenvironment
-
Via CD8 boost with aPD-1 and APD l-1 checkpoint blockers
-
-
Hiltonol® activates Immunological memory, facilitating durable tumor responses
bottom of page